* "Enough is enough", says seven-time Tour de France winner
* Debate begins on whether cyclist is guilty
* Endorsement opportunities in question
Aug 24 Lance Armstrong was stripped of his record seven Tour de France wins and handed a lifetime ban by the United States Anti-Doping Agency on Friday, but he remained defiant as supporters rallied around the American cyclist.
Saying that "enough is enough," Armstrong issued a statement late on Thursday indicating that would not challenge USADA charges he had doped throughout his career, although he continued to deny he had ever used performance-enhancing drugs.
While the USADA can remove Armstrong's titles, such a decision could ultimately rest with the Court of Arbitration for Sport in Lausanne, Switzerland, should the International Cycling Union challenge the USADA's ruling.
But weary from years of denial, legal battles and skirmishes with former teammates and anti-doping chiefs, Armstrong said it was a fight he no longer had the stomach for.
"Today I will turn the page," Armstrong said. "I will no longer address this issue regardless of the circumstances."
Less than 24 hours after issuing that statement, Armstrong was planning 'business as usual' with a weekend bike ride in Colorado, tweeting: "Excited to be racing the #poweroffour tomorrow here in @AspenCO. 9000 vert in just 36 miles!"
Armstrong may have turned the page but the story is far from over.
One of the sporting world's most polarizing figures, Armstrong remains a hero to millions of cancer survivors for beating the disease and coming back to win the Tour de France seven times. To others, he is a drug cheat and fraud.
World Anti-doping Agency chief John Fahey said Armstrong's decision not to contest the allegations added up to nothing more than an admission of guilt.
"He had the right to rip up those charges, but he elected not to. Therefore the only interpretation in these circumstances is that there was substance in those charges," Fahey told Reuters in a telephone interview on Friday.
Bill Stapleton, Armstrong's agent for 17 years, strongly disagreed.
"This is not an admission of guilt, this is a rebuke of a process that is disgusting and unfair," Stapleton said. "We believe they're completely out of bounds.
"We've been clear that we don't think they (USADA) have the authority to do that and we'll see what the people who run the Tour de France and the International Federation of Cycling have to say about that."
The debate over Armstrong's guilt will now rage, with some heavy hitters like longtime sponsor Nike, the world's biggest sportswear maker, lining up alongside the disgraced cyclist, while anti-doping crusaders claim victory.
Since 2004, Nike has helped Livestrong, Armstrong's organization to help cancer survivors, raise over $100 million for cancer research and created the Livestrong yellow wristbands that became a global phenomenon with over 84 million bands distributed.
"Lance has stated his innocence and has been unwavering on this position. Nike plans to continue to support Lance and the Lance Armstrong Foundation, a foundation that Lance created to serve cancer survivors," the company said in a statement.
Armstrong, 40, has been one of the most successful and controversial cyclists of all time, returning to the sport after beating cancer to win the Tour de France seven straight times, from 1999 to 2005.
Livestrong takes its inspiration from his achievements and recovery from testicular cancer that made him a hero to many and boosted the sport's popularity in the United States.
The Lance Armstrong Foundation, which raised $51 million in 2011, said it received 400 donations totaling $75,000 on Friday, 20 times more than the amount donated on Thursday.
Armstrong also made many enemies throughout his career, with several of his former teammates and colleagues allegedly ready to testify that he doped.
Former teammate and deposed Tour de France winner Floyd Landis accused Armstrong in 2010 of using performance-enhancing drugs and teaching others how to avoid being caught.
In a bizarre coincidence of timing, Landis appeared in federal court in San Diego, California, on Friday and entered a deferred prosecution agreement in which he admitted defrauding 1,765 individuals who donated money to the Floyd Fairness Fund. The cyclist agreed to pay $478,354 in restitution.
Armstrong also has his loyalists, such as Jim Ochowicz, director of the BMC cycling team and a longtime friend who helped him when he was an amateur rider and young professional.
"As a friend of Lance's, I support his decision to call it an end," said Ochowicz. "He has done so much for our sport over the years, and I am sad at what has transpired.
"I love him. I know he still has a big fight ahead of him and his battle of trying to find a cure for cancer and help survivors and carry on with the Lance Armstrong foundation.
"I think he has earned every victory he's had," he said.
The USADA believes, however, it has enough compelling evidence to prove Armstrong did not claim his victories fairly.
A quasi-governmental agency created by the U.S. Congress in 2000, the USADA formally charged Armstrong in June with doping and taking part in a conspiracy with members of his championship teams.
EVIDENCE AGAINST ARMSTRONG IN HAND
The agency said in a letter to Armstrong that it had blood samples from 2009 and 2010 that were "fully consistent" with doping.
Michael McCann, an expert in sports law at Vermont Law School, said Armstrong's decision not to contest the USADA charges in arbitration might have been the cyclist's best option in the face of mounting circumstantial evidence.
"This gives his supporters reason to support him," McCann told Reuters. "If he had gone to arbitration and lost - which I think almost definitely would have happened - from a public relations standpoint, that would have been much more harmful."
In losing his titles, Armstrong joins Canadian Ben Johnson and American Marion Jones as the highest-profile athletes to lose championships as a result of doping sanctions.
Johnson was stripped of the 1988 Seoul Olympics 100 metres title after testing positive for a steroid. while Jones lost her 2000 Sydney Olympics 100, 200 and 4x400 metres relay gold medals when she confessed she had been taking drugs at the time.
Armstrong faces the possibility of legal action from promoters and race organizers looking to recover prize money.
It also remains to be seen what impact the USADA's action will have on his endorsement potential and ability to keep raising funds for his foundation.
Despite having his reputation tarnished, Armstrong's triumph over cancer and fundraising efforts make him a valuable pitchman, marketing experts said.
While Nike was quick to stand by Armstrong, his other sponsors, including RadioShack, exercise bike maker Johnson Health Tech, sunglass maker Oakley, owned by Italy's Luxottica, and Michelob, made by Anheuser-Busch InBev, have not leapt to his defence.
Robert Boland, professor of sports management at New York University, said Armstrong's extensive work on cancer would help blunt the impact of the lost titles.
"His story has not been diminished. Here's a guy who essentially was at death's door with cancer and came back. That example still makes him very compelling," he said.
Still, Boland said it would be difficult for Armstrong to continue to endorse bicycles or bicycle equipment, since he is now banned from competitions.
"If he can't show up at certain events, how do you use him?"
With the possibility each of his seven Tour de France crowns could go to other riders, Armstrong maintained that no matter what the USADA had ruled, those he competed with would always know he was the true winner.
Spain's Fernando Escartin, who will rise to second from third in the 1999 Tour de France after the USADA's decision, said the American would always be the champion.
"For me, Lance Armstrong remains the 1999 Tour winner, second (Alex) Zulle and third, me," the now-retired Escartin told Reuters at the Vuelta a Espana race on Friday.
"It's 13 years now since this all happened. It seems completely illogical and unreal. I don't want to even think about it."
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