UPDATE 4-Iran to hold war games to protect nuclear facilities

* Iran to hit back at Tel Aviv if attacked - cleric

* Iranian military to hold five days of war games

* Commander sees "Zionist" pressure on Russia over S-300

* Says Iran can produce advanced defence missiles itself (Recasts with cleric's comment on retaliation for any attack)

By Fredrik Dahl and Hashem Kalantari

TEHRAN, Nov 21 (Reuters) - Iran's military said it will begin large-scale air defence drills on Sunday, and a cleric in the Revolutionary Guards warned that the Islamic Republic would fire missiles at "the heart of Tel Aviv" if attacked.

The war games, due to last five days, are intended to help protect Iran's nuclear facilities, Iranian media reported, citing Brigadier General Ahmad Mighani.

The statements came a day after senior officials from six world powers said they were disappointed Iran had not accepted proposals intended to delay its potential to make nuclear weapons, and urged Tehran to reconsider.

The United States, Russia, China, Germany, Britain and France met after U.S. President Barack Obama warned there could be a package of sanctions against Iran within weeks.