FACTBOX - Profiles of U.S. presidential hopefuls

(Reuters) - Leading candidates in the race for the November 2008 U.S. presidential election are seeking to become the first woman, first black, first Mormon or oldest first-term president to occupy the White House.

Following are brief profiles of the main contenders:

DEMOCRATS:

HILLARY CLINTON, 60, would be the first woman U.S. president. Is a senator from New York and was first lady when her husband, Bill, was president from 1993 to 2001. Has emphasized efforts to insure 47 million Americans without health coverage and criticized opponents for lack of experience. Has led most national opinion polls by double digits but is locked in tight fights in Iowa and New Hampshire.

JOHN EDWARDS, 54, is a former one-term senator from North Carolina and was the Democratic nominee for vice president in 2004. Has made combating poverty a major campaign theme. Called his voting to authorize military action in Iraq a mistake and now urges withdrawing U.S. troops from Iraq. His wife, Elizabeth, is being treated for a recurrence of cancer.

BARACK OBAMA, 46, is a first-term U.S. senator representing Illinois and would be the first black president. Gave the keynote address at the 2004 Democratic convention before he was elected to the Senate. Has opposed the Iraq war from the beginning and tried to cast himself as a Washington outsider. Has pulled nearly even with front-running Clinton in recent polls in Iowa and New Hampshire but trails nationally.

REPUBLICANS:

RUDY GIULIANI, 63, is a former New York mayor and has tried to boost his candidacy by speaking repeatedly about his leadership during the September 11 attacks. Widely shunned by many conservatives because of his support for abortion rights, gun control and gay rights, but received endorsement from Christian evangelist Pat Robertson. Has led most national polls but is behind in early primary voting states.

MIKE HUCKABEE, 52, is a bass-playing former Arkansas governor and Baptist minister from Hope, Arkansas, the birthplace of Bill Clinton. Has used his religious beliefs and support for constitutional bans on gay marriage and abortion to boost support from conservative voters. Known for his wit, but criticized for lack of knowledge on foreign policy.