Drug and vaccine makers on standby over swine flu

By Ben Hirschler and Sam Cage

LONDON/ZURICH (Reuters) - Drugmakers said on Sunday they could supply millions of doses of medicine and were ready to work on a vaccine against a new type of swine flu that has killed up to 81 people in Mexico and infected around a dozen in the United States.

Roche Holding AG's Tamiflu, known generically as oseltamivir, and GlaxoSmithKline Plc's Relenza, or zanamivir, are both recommended drugs for seasonal flu and have been shown to work against viral samples of the new disease.

Tamiflu is expected to be in greatest demand should swine flu develop into a pandemic, as experts fear it may, since it is given as a tablet. Relenza must be inhaled.

Roche said it has a stockpile of 3 million packages of Tamiflu ready for use by the World Health Organisation (WHO), half held in the United States and half in Switzerland.

"So far the WHO has not requested we deploy this stockpile. Of course, as soon as the WHO requires that we deploy it we will do so," said Roche spokeswoman Claudia Schmitt.

Both Roche and Glaxo said they were in contact with the WHO, U.S. authorities and the government in Mexico.

The two companies have received contracts in recent years from individual governments and corporations for stockpiles of their medicines, following earlier fears over bird flu.

Those sales provided windfall profits, especially for Roche, and also benefited their respective partners. Tamiflu was originally invented by U.S. biotech company Gilead Sciences Inc , while Relenza was licensed to Glaxo by Australia's Biota Holdings Ltd.