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UPDATE 3-U.S. approves Roche drug that targets severe form of MS

* Biogen to get royalties for its share in drug (Recasts story to focus on new treatment for PPMS, adds company, analysts and MS Society comments)

2:26pm BST

BRIEF-Invent Medic Sweden: rights issue oversubscribed

* RIGHTS ISSUE WAS SUBSCRIBED TO ABOUT 19 MILLION SWEDISH CROWNS, CORRESPONDING TO A SUBSCRIPTION RATE OF ABOUT 186 PERCENT

2:20pm BST

Singapore confirms two new cases of Zika virus

SINGAPORE, March 29 Singapore has confirmed two cases of locally transmitted infections of the Zika virus in a northeastern part of the city state, the National Environment Agency said on Wednesday, describing it as the first Zika cluster of 2017.

2:00pm BST

BRIEF-Guangxi Wuzhou Zhongheng's 2016 net profit down 5.9 pct y

* Says 2016 net profit down 5.9 percent y/y at 489.4 million yuan ($71.05 million)

1:44pm BST

BRIEF-Innoviva board sends letter to shareholders

* Innoviva board sends letter to shareholders; board recommends Innoviva shareholders "support company's strategy and board" Source text for Eikon: Further company coverage:

1:42pm BST

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