July 20, 2020 / 3:36 PM / 12 days ago

FACTBOX- The race for a coronavirus vaccine

 (Adds Osaka University, Kentucky Bioprocessing, Vaxine, Medigen; Updates CureVac, J&J, GSK)
    July 29 (Reuters) - More than 150 vaccines are being developed and tested around the world to stop the COVID-19 pandemic, with 25 in human
clinical trials, according to the World Health Organization. 
    The following list tracks the latest developments from major drugmakers and research institutes that have started human trials for their
vaccine candidates.
    For a separate FACTBOX on treatments under development, click here:
   
 Company                      State of play                                        Development phase                         Story date/link
 AstraZeneca Plc              Vaccine produces immune response in early-stage      Final stage study in 1,077 healthy        July 20             
                              trials; Late-stage trials currently underway in      adults                                    
                              Brazil and South Africa and due to start in the                                                
                              U.S. ; Over a million doses possible by September                                              
 Sinopharm                    The Chinese state-owned company is developing two    Final stage trials in Abu Dhabi, testing  July 16             
                              vaccines, one of which has shown promise in humans.  up to 15,000 volunteers.                  
 Pfizer Inc         and       Vaccine produced virus-neutralizing antibodies in    Begins pivotal global study to evaluate   July 27             
 BioNTech SE                  early-stage trials in U.S. and Germany; Pfizer aims  lead COVID-19 vaccine candidate; Study    
                              for about 1.3 billion doses by the end of 2021       aims to enroll 30,000 volunteers          
 Moderna Inc                  Vaccine could be ready for widespread use by end of  30,000-subject final stage trial to       July 27             
                              2020, company says on track to deliver up to 1       demonstrate it is safe and effective      
                              billion doses a year, beginning 2021                 began on July 27.                         
 Sinovac Biotech Ltd          The China-based vaccine maker has released positive  Final-stage trials.                       July 6             
                              preliminary results from early-stage trials of its                                             
                              vaccine.                                                                                       
 CanSino Biologics            Early results showed the China-based company's       Mid-stage trial.                          July 20             
                              vaccine is safe. China's military has received the                                             
                              greenlight to use the vaccine.                                                                 
 Inovio Pharma                Vaccine candidate, found to be safe, induced immune  Mid-stage testing.                        June 30             
                              responses in healthy volunteers in an early stage                                              
                              study                                                                                          
 Not applicable               Researchers at Institute of Medical Biology at       Mid-stage trials.                         June 21             
                              Chinese Academy of Medical Sciences are testing a                                              
                              coronavirus vaccine.                                                                           
 Chongqing Zhifei Biological  The Chinese company's unit Anhui Zhifei Longcom      Mid-stage trial.                          July 10             
 Products                     Biopharmaceutical has begun human trials.                                                      
 Bharat Biotech               Vaccine approved for human trials in India.          Early- to mid-stage trials to start in    June 29             
                                                                                   July                                      
 Johnson & Johnson            In talks with Japan, Bill and Melinda Gates          Early stage trials to start in July,      July 16             
                              Foundation, and the European Union for vaccine       late-stage study planned for September.   
                              allocations, Reuters reported.                                                                 
 Novavax Inc                  The U.S.  government has awarded $1.6 billion to     Early-stage testing.                      July 7             
                              test and manufacture its experimental vaccine.                                                 
 GlaxoSmithKline Plc          Partnered with Sanofi SA           to develop a      Early stage trials to begin in            July 29             
                              vaccine.                                             September.                                
 CureVac                      German biotech expects data in September or          Early-stage trial.                        July 24             
                              October; files for IPO in U.S.                                                                 
 Clover Biopharmaceuticals    The Chinese developer received $66 million in        Early-stage trials.                       July 8             
                              investment from an epidemic response group.                                                    
 Not applicable               Scientists at Imperial College London are running    Early-stage trials.                       June 15             
                              trials of a potential coronavirus vaccine.                                                     
 Genexine Inc                 South Korea's Genexine has begun human trials of     Early-stage trials.                       June 19             
                              its vaccine.                                                                                   
 Not applicable               The Gamaleya Research Institute in Russia has begun  Early-stage trials                        July 13             
                              human trials of an experimental vaccine,  with                                                 
                              results expected in August.                                                                    
 Walvax Biotechnology Co      Trials sponsored by the China-based company, along   Early-stage studies.                      June 24             
                              with a Chinese military research institute, have                                               
                              begun.                                                                                         
 Medicago                     The Canadian company is studying a plant-based       Early-stage trials.                       July 14             
                              vaccine.                                                                                       
 Cadila Healthcare Ltd        Plans to finish late-stage trials by early 2021.     Early-stage trials.                       July 17             
                                                                                                                             
 Not applicable               University of Queensland began human trials in       Early-stage testing.                      July 14 (bit.ly/2Eo5iDg)
                              collaboration with Australian biotech company CSL                                              
                                                                                                                             
 Arcturus Therapeutics        Gets approval to begin clinical trials for its       Early-stage testing.                      July 21            
          and Duke-NUS        COVID-19 vaccine candidate, LUNAR-COV19                                                        
 Osaka University, AnGes,     A single-center trial in 30 healthy volunteers       Early-stage testing.                      June 29 (bit.ly/3gaEiFB)
 Takara Bio                                                                                                                  
 Kentucky BioprocessingInc    Expects to begin trial of vaccine candidate in 180   Early-stage testing.                      July 28 (bit.ly/2BJDU1M)
                              adults on July 31                                                                              
 Vaxine Pty Ltd/Medytox       Australian biotech expects to start mid-stage        Early-stage testing.                      July 29             
                              trials in next few weeks after positive results                                                
                              from the first stage human study                                                               
 Medigen Vaccine Biologics    Expects to begin early-stage study in 45 people on   Early-stage trial.                        July 27 (bit.ly/2XbnAOS)
 Corp/NIAID/Dynavax           Sept 1. Not yet recruiting                                                                     
 
 (Reporting by Vishwadha Chander and Manas Mishra in Bengaluru; Editing by Sriraj Kalluvila. Shailesh Kuber and Maju Samuel)
  
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