March 11, 2015 / 2:26 PM / 5 years ago

Trial of Tekmira's TKM-Ebola treatment starts in Sierra Leone

A health worker in protective gear walks inside a Red Cross facility in the town of Koidu, Kono district in Eastern Sierra Leone December 19, 2014. REUTERS/Baz Ratner

LONDON (Reuters) - A clinical trial of Tekmira’s experimental drug TKM-Ebola-Guinea will start on Wednesday in Sierra Leone, Britain’s Wellcome Trust global health charity said.

The drug, a so-called “synthetic small interfering RNA (siRNA) therapeutic”, is designed specifically to target the strain of Ebola virus causing a vast epidemic centered mainly in Guinea, Liberia and Sierra Leone.

An earlier version of the TKM-Ebola drug — targeted at a different strain — has already been tested in healthy human volunteers.

The efficacy of the Guinea version will now be tested in Ebola patients in a fast-tracked trial funded by Wellcome, with results expected in the second half of this year, the charity said in a statement.

Reporting by Kate Kelland, editing by Ben Hirschler

0 : 0
  • narrow-browser-and-phone
  • medium-browser-and-portrait-tablet
  • landscape-tablet
  • medium-wide-browser
  • wide-browser-and-larger
  • medium-browser-and-landscape-tablet
  • medium-wide-browser-and-larger
  • above-phone
  • portrait-tablet-and-above
  • above-portrait-tablet
  • landscape-tablet-and-above
  • landscape-tablet-and-medium-wide-browser
  • portrait-tablet-and-below
  • landscape-tablet-and-below