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Roche Holding AG (RO.S)

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Latest Key Developments (Source: Significant Developments)

Abbvie Receives Positive CHMP Opinion Fo Chemotherapy-Free Combination Of Venclyxto With Rituximab
12:28pm BST 

Sept 21 (Reuters) - AbbVie Inc ::ABBVIE RECEIVES POSITIVE CHMP OPINION FOR A NOVEL, CHEMOTHERAPY-FREE COMBINATION OF VENCLYXTO® (VENETOCLAX TABLETS) WITH RITUXIMAB AS A TREATMENT WITH A FIXED DURATION FOR PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA WHO HAVE RECEIVED AT LEAST ONE PRIOR THERAPY.ABBVIE - SAFETY PROFILE OF COMBINATION OF VENCLYXTO PLUS RITUXIMAB IS CONSISTENT WITH KNOWN SAFETY PROFILE OF EACH MEDICINE ALONE.  Full Article

Affimed To Collaborate With Genentech To Develop Novel Nk Cell Engager-Based Immunotherapeutics
Monday, 27 Aug 2018 

Aug 27 (Reuters) - Affimed NV ::AFFIMED ANNOUNCES COLLABORATION WITH GENENTECH TO DEVELOP NOVEL NK CELL ENGAGER-BASED IMMUNOTHERAPEUTICS FOR MULTIPLE CANCER TARGETS.AFFIMED NV - TO RECEIVE $96 MILLION UPFRONT AND COMMITTED FUNDING AND IS ELIGIBLE FOR UP TO AN ADDITIONAL $5.0 BILLION INCLUDING MILESTONE PAYMENTS.AFFIMED NV - ADDITIONAL $5.0 BILLION CO MAY RECEIVE ALSO INCLUDES ROYALTIES ON SALES.  Full Article

Genentech Says FDA Grants Breakthrough Therapy Designation For Xolair (Omalizumab) For Food Allergies
Monday, 13 Aug 2018 

Aug 13 (Reuters) - Genentech Inc::FDA GRANTS BREAKTHROUGH THERAPY DESIGNATION FOR XOLAIR (OMALIZUMAB) FOR FOOD ALLERGIES.  Full Article

Hoffmann-La Roche Ltd - Health Canada Has Approved Hemlibra (Emicizumab Injection)
Tuesday, 7 Aug 2018 

Aug 7 (Reuters) - Roche Holding AG ::HOFFMANN-LA ROCHE LIMITED - HEALTH CANADA HAS APPROVED HEMLIBRA (EMICIZUMAB INJECTION) FOR HEMOPHILIA A (CONGENITAL FACTOR VIII DEFICIENCY) PATIENTS.  Full Article

Puretech Health Announces Collaboration With Roche
Friday, 20 Jul 2018 

July 20 (Reuters) - PureTech Health PLC ::PURETECH HEALTH ANNOUNCES COLLABORATION WITH ROCHE TO ADVANCE TECHNOLOGY FOR ORAL ADMINISTRATION OF ANTISENSE OLIGONUCLEOTIDES.PURETECH HEALTH PLC - PURETECH HEALTH TO RECEIVE UP TO $36 MILLION IN UPFRONT PAYMENTS, RESEARCH SUPPORT, AND EARLY PRECLINICAL MILESTONES.PURETECH HEALTH PLC - PURETECH HEALTH ALSO ELIGIBLE TO POTENTIALLY RECEIVE OVER $1 BILLION IN DEVELOPMENT MILESTONES.  Full Article

Celgene Corp Says Phase III Impassion130 Study Met Co-Primary Endpoint Of Progression-Free Survival
Tuesday, 10 Jul 2018 

July 10 (Reuters) - Celgene Corp ::ANTI-PD-L1 IMMUNOTHERAPY PLUS ABRAXANE® SIGNIFICANTLY REDUCED THE RISK OF DISEASE WORSENING OR DEATH IN PATIENTS WITH METASTATIC OR LOCALLY ADVANCED TRIPLE NEGATIVE BREAST CANCER IN PHASE III IMPASSION130 STUDY.CELGENE CORP - PHASE III IMPASSION130 STUDY, WHICH WAS SPONSORED BY ROCHE, MET ITS CO-PRIMARY ENDPOINT OF PROGRESSION-FREE SURVIVAL.CELGENE - OVERALL SURVIVAL IS ENCOURAGING IN PD-L1 POSITIVE POPULATION AT INTERIM ANALYSIS, FOLLOW UP WILL CONTINUE UNTIL NEXT PLANNED ANALYSIS.CELGENE CORP - SAFETY IN TECENTRIQ PLUS ABRAXANE ARM APPEARED CONSISTENT WITH KNOWN SAFETY PROFILES OF INDIVIDUAL MEDICINES.CELGENE CORP - NO NEW SAFETY SIGNALS WERE IDENTIFIED WITH IN TECENTRIQ PLUS ABRAXANE COMBINATION.CELGENE CORP - DATA DEMONSTRATE POTENTIAL ROLE OF ABRAXANE AS PREFERRED CHEMOTHERAPY PARTNER FOR IMMUNOTHERAPY COMBINATIONS.  Full Article

Roche Diagnostics Formally Asks Health Canada To Review Its Harmony Test
Wednesday, 27 Jun 2018 

June 27 (Reuters) - Roche Diagnostics::ROCHE DIAGNOSTICS SAYS HAS FORMALLY ASKED HEALTH CANADA TO REVIEW ITS HARMONY TEST, WHICH IS A BLOOD SCREENING TEST FOR PREGNANT WOMEN.  Full Article

PeptiDream announces expansion of discovery alliance with Genentech
Monday, 25 Jun 2018 

June 25 (Reuters) - PeptiDream Inc <4587.T>:Says it announced today the expansion of its ongoing discovery and optimization collaboration with U.S.- based Genentech .  Full Article

FDA Approves Abbvie & Genentech USA's VENCLEXTA For Treating Two Types Of Blood Cancers
Friday, 8 Jun 2018 

June 8 (Reuters) - U.S. Food and Drug Administration::U.S. FDA SAYS APPROVED ABBVIE & GENENTECH USA'S VENCLEXTA FOR TREATING PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA OR SMALL LYMPHOCYTIC LYMPHOMA.  Full Article

Five Prime Therapeutics Announces Collaboration With Roche
Wednesday, 30 May 2018 

May 30 (Reuters) - Five Prime Therapeutics Inc ::FIVE PRIME THERAPEUTICS ANNOUNCES COLLABORATION WITH ROCHE TO DEVELOP COMPANION DIAGNOSTICS FOR TARGETED IMMUNO-ONCOLOGY INVESTIGATIONAL DRUG CANDIDATES.FIVE PRIME THERAPEUTICS INC - FINANCIAL TERMS OF AGREEMENT WERE NOT DISCLOSED..  Full Article

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Doctors win battle with drug giants over cheaper eye medicine

ZURICH Drug giants Novartis , Bayer and Roche on Friday lost a bid to stop British doctors from recommending a cheaper drug option for people with an eye disease that causes blindness, the High Court in London ruled.