Reuters - Video

EDITION: U.S. | U.K. | IN

Technology

Researchers cure diabetes in mice

Wednesday, March 05, 2014 - 02:04

Mar. 5 - Researchers in California have turned skin cells in mice into insulin producing beta cells, effectively curing the animals of diabetes. They hope to achieve similar results in human cells, paving the way to an eventual cure for a disease that affects millions of people around the world. Ben Gruber has more.

▲ Hide Transcript

View Transcript

Just a few weeks ago this mouse had diabetes. But thanks to groundbreaking research taking place at the Gladstone Institute in San Francisco, the mouse is now disease free. The research, led by Dr. Sheng Ding, uses a new method to decode and genetically modify skin cells into insulin producing beta cells. Director of the Institute, Dr. Deepak Srivastava says Dr. Ding's research paves the way to developing a new way to battle diabetes. (SOUNDBITE) (English) DR. DEEPAK SRIVASTAVA, DIRECTOR AT THE GLADSTONE INSTITUTE, SAYING: "He has been able to create a cell that is not a stem cell but is derived from, in this case, an animals' own cell and transplant it back into the animals and have it essentially cure its diabetes." To accomplish this, the researchers extracted skin cells from the mouse and used a two phase process to reprogram them into what they call PPLC cells. And just eight weeks after these new cells were transplanted into the pancreas of the mouse, they matured into insulin producing beta cells that soon began regulating the animal's blood sugar levels, essentially curing it of diabetes. Dr. Srivastava says his team are now testing the reprogramming protocol on human cells to see if they respond in the same way. (SOUNDBITE) (English) DR. DEEPAK SRIVASTAVA, DIRECTOR AT THE GLADSTONE INSTITUTE, SAYING: "I think this is a major step forward because we haven't has this type of success even in an animal model in the past. There will be many hurdles ahead to see of this works in humans and test all of the safety issues. But there is reason for a lot of hope for the millions of people out there suffering from diabetes." Improving technologies are increasingly helping diabetics monitor glucose levels in their blood and manage their disease, but the Gladstone scientists believe that while there are years of research still ahead, they may be on track to produce a cure.

Press CTRL+C (Windows), CMD+C (Mac), or long-press the URL below on your mobile device to copy the code

Researchers cure diabetes in mice

Wednesday, March 05, 2014 - 02:04

Editors' Picks »

Moving Pictures »

Images of September Images of September

Thu, 02 Oct, 2014 - (1:00)

Still missing – MH370 Still missing – MH370

Fri, 05 Sep, 2014 - (2:05)

Burning Together Burning Together

Mon, 01 Sep, 2014 - (2:23)

Mending dolls, teddies and hearts Mending dolls, teddies and hearts

Fri, 22 Aug, 2014 - (3:12)

Images of August Images of August

Fri, 29 Aug, 2014 - (1:00)

"Old timers" sail the Chesapeake Bay "Old timers" sail the Chesapeake Bay

Mon, 11 Aug, 2014 - (2:27)

Burned memories Burned memories

Fri, 08 Aug, 2014 - (3:02)

Images of July Images of July

Fri, 01 Aug, 2014 - (1:20)

World Cup: passion on the pitch World Cup: passion on the pitch

Fri, 11 Jul, 2014 - (1:00)

Reuters Investigates »

Re-homing victim: "I could have been dead" Re-homing victim: "I could have been dead"

Wed, 19 Feb, 2014 - (8:24)

Cops and loggers in the Amazon rainforest Cops and loggers in the Amazon rainforest

Fri, 10 Jan, 2014 - (4:01)

"Passed around like a dog" "Passed around like a dog"

Thu, 29 Aug, 2013 - (6:32)

Adopted, then abandoned online Adopted, then abandoned online

Thu, 29 Aug, 2013 - (13:21)

How the DEA keeps its secrets secret How the DEA keeps its secrets secret

Mon, 05 Aug, 2013 - (1:36)

How education lost its role as the great equalizer - Reuters Investigates How education lost its role as the great...

Mon, 17 Dec, 2012 - (7:52)

Jihad Jane: From abused child to American jihadist - Reuters Investigates Jihad Jane: From abused child to American...

Sun, 09 Dec, 2012 - (10:01)

Jihad Jane: The order to kill - Reuters Investigates Jihad Jane: The order to kill - Reuters...

Mon, 10 Dec, 2012 - (10:39)